In Q4 2025, Driehaus Capital held 293 positions worth $11.3B. They initiated 46 new positions and exited 487. Their largest holding was CRNX ($297.3M).
Portfolio Value (13F)
$11.3B
Holdings
293
Top 10 Concentration
17.3%
QoQ Change
N/A
Turnover
8.5%
Sector Breakdown
Biotechnology95%(275)
Other Healthcare5%(18)
Q4 2025 Holdings (293)
| # | Ticker | Company | Change | Value | % of Portfolio | SI % Float ? |
|---|---|---|---|---|---|---|
| 1 | CRNX | Crinetics Pharmaceuticals Inc. | Decreased | $297.3M | 2.62% | 15.7% |
| 2 | PRAX | Praxis Precision Medicines, Inc. | Increased | $275.0M | 2.43% | 13.6% |
| 3 | GH | Guardant Health Inc. | Decreased | $218.9M | 1.93% | 10.1% |
| 4 | XENE | Xenon Pharmaceuticals Inc. | Increased | $203.4M | 1.79% | 4.3% |
| 5 | PL-WT | Planet Labs PBC | New | $182.0M | 1.61% | — |
| 6 | PL | Planet Labs PBC | New | $167.8M | 1.48% | — |
| 7 | APGE | Apogee Therapeutics Inc. | Increased | $164.8M | 1.45% | 19.9% |
| 8 | EOSE | Eos Energy Enterprises, Inc. | Increased | $163.5M | 1.44% | 30.3% |
| 9 | SITM | Sitime Corp. | Decreased | $145.8M | 1.29% | 6.9% |
| 10 | NTRA | Natera Inc. | Increased | $143.4M | 1.26% | 2.7% |
| 11 | CCJ | Cameco Corp. | Decreased | $139.3M | 1.23% | — |
| 12 | FTAIN | FTAI Aviation Ltd. | Increased | $137.9M | 1.22% | — |
| 13 | RYTM | Rhythm Pharmaceuticals Inc. | Decreased | $137.6M | 1.21% | 14.6% |
| 14 | HDB | Hdfc Bank Ltd. | Increased | $136.0M | 1.20% | 0.3% |
| 15 | BAP | Credicorp Ltd. | Increased | $135.5M | 1.19% | 2.3% |
| 16 | SEPN | Septerna, Inc. | Decreased | $134.1M | 1.18% | 9.1% |
| 17 | BBIO | BridgeBio Pharma Inc. | Increased | $128.6M | 1.13% | 13.7% |
| 18 | PI | Impinj Inc. | Increased | $128.3M | 1.13% | 14.8% |
| 19 | CRS | Carpenter Technology Corp. | Increased | $127.0M | 1.12% | 3.9% |
| 20 | IBN | Icici Bank Ltd. | Decreased | $121.1M | 1.07% | 1.4% |
| 21 | IDCC | InterDigital, Inc. | Increased | $119.4M | 1.05% | 12.6% |
| 22 | XMTR | Xometry, Inc. | Increased | $118.1M | 1.04% | 10.2% |
| 23 | ARWR | Arrowhead Pharmaceuticals Inc. | Decreased | $117.5M | 1.04% | 12.0% |
| 24 | NHCOther Healthcare | National Healthcare Corp. | Increased | $116.5M | 1.03% | 6.0% |
| 25 | GPCR | Structure Therapeutics Inc. | Increased | $114.2M | 1.01% | 11.5% |
| 26 | WVE | Wave Life Sciences Ltd. | Increased | $111.9M | 0.99% | 9.1% |
| 27 | FN | Fabrinet | Decreased | $109.7M | 0.97% | 10.0% |
| 28 | WFRD | Weatherford International plc | Increased | $108.3M | 0.96% | 7.7% |
| 29 | EWTX | Edgewise Therapeutics, Inc. | Increased | $104.0M | 0.92% | 13.3% |
| 30 | EMBJ | Embraer S.A. | Increased | $102.3M | 0.90% | 1.1% |
| 31 | KRMN | Karman Holdings Inc. | Decreased | $99.2M | 0.87% | 7.2% |
| 32 | PTGX | Protagonist Therapeutics Inc. | Decreased | $96.0M | 0.85% | 15.7% |
| 33 | TARS | Tarsus Pharmaceuticals Inc. | Increased | $96.0M | 0.85% | 11.6% |
| 34 | CVNA | Carvana CO. | Decreased | $95.8M | 0.84% | 13.5% |
| 35 | SYRE | Spyre Therapeutics, Inc. | Increased | $94.4M | 0.83% | 15.1% |
| 36 | CR | Crane Co | Decreased | $93.3M | 0.82% | 1.6% |
| 37 | VSECU | Vse Corp. | Increased | $89.9M | 0.79% | — |
| 38 | RMBS | Rambus Inc. | Increased | $87.7M | 0.77% | 8.5% |
| 39 | TMDXOther Healthcare | TransMedics Group, Inc. | Decreased | $86.6M | 0.76% | 34.4% |
| 40 | PTCT | PTC Therapeutics Inc. | Increased | $86.3M | 0.76% | 16.0% |
| 41 | SRRK | Scholar Rock Holding Corp. | Increased | $86.0M | 0.76% | 15.7% |
| 42 | ITUB | Itau Unibanco Holding S.A. | Increased | $84.9M | 0.75% | 0.4% |
| 43 | KYMR | Kymera Therapeutics Inc. | Increased | $83.2M | 0.73% | 15.2% |
| 44 | COHR | Coherent Corp. | Increased | $82.7M | 0.73% | 6.1% |
| 45 | CPA | Copa Holdings, S.A. | Increased | $80.9M | 0.71% | 5.7% |
| 46 | IMNM | Immunome Inc. | Increased | $79.6M | 0.70% | 19.3% |
| 47 | AXON | Axon Enterprise, Inc. | Decreased | $77.4M | 0.68% | 4.5% |
| 48 | AVAV | AeroVironment Inc. | Decreased | $77.4M | 0.68% | 11.8% |
| 49 | RSI | Rush Street Interactive, Inc. | Decreased | $75.6M | 0.67% | 7.0% |
| 50 | ROAD | Construction Partners, Inc. | Decreased | $75.3M | 0.66% | 6.0% |
| 51 | ARQT | Arcus Biosciences Inc. | Increased | $74.4M | 0.66% | 14.4% |
| 52 | PAY | Paymentus Holdings, Inc. | Decreased | $70.7M | 0.62% | 4.7% |
| 53 | SMTC | Semtech Corp. | Increased | $68.6M | 0.61% | 7.8% |
| 54 | FLS | Flowserve Corp. | Decreased | $67.8M | 0.60% | 3.8% |
| 55 | GGAL | Grupo Financiero Galicia SA | Increased | $66.7M | 0.59% | 20.5% |
| 56 | LC | LendingClub Corp. | Decreased | $66.7M | 0.59% | 5.4% |
| 57 | HCIIP | HCI Group, Inc. | Decreased | $66.4M | 0.59% | — |
| 58 | MDGL | Madrigal Pharmaceuticals Inc. | Decreased | $65.0M | 0.57% | 20.2% |
| 59 | MOD | Modine Manufacturing CO | Decreased | $64.1M | 0.57% | 7.0% |
| 60 | BOOT | Boot Barn Holdings, Inc. | Decreased | $63.6M | 0.56% | 12.3% |
| 61 | PAASF | Pan American Silver Corp. | Decreased | $61.6M | 0.54% | — |
| 62 | ATECOther Healthcare | Alphatec Holdings, Inc. | Increased | $60.1M | 0.53% | 8.9% |
| 63 | OSIS | Osi Systems Inc. | Increased | $60.1M | 0.53% | 15.4% |
| 64 | STRL | Sterling Infrastructure, Inc. | Decreased | $59.6M | 0.53% | 8.4% |
| 65 | LEU | Centrus Energy Corp. | Decreased | $59.3M | 0.52% | 22.9% |
| 66 | SEI | Solaris Energy Infrastructure, Inc. | Increased | $56.4M | 0.50% | 22.8% |
| 67 | CUBB | Customers Bancorp, Inc. | Increased | $56.0M | 0.49% | — |
| 68 | CRDO | Credo Technology Group Holding Ltd. | Decreased | $55.2M | 0.49% | 5.8% |
| 69 | ONTO | Onto Innovation Inc. | Increased | $55.1M | 0.49% | 3.0% |
| 70 | GRABW | Grab Holdings Ltd. | Increased | $54.9M | 0.48% | — |
| 71 | IAG | Iamgold Corp. | Increased | $54.0M | 0.48% | — |
| 72 | MIR | Mirion Technologies, Inc. | Increased | $53.8M | 0.47% | 13.1% |
| 73 | IBP | Installed Building Products, Inc. | Decreased | $53.8M | 0.47% | 7.4% |
| 74 | ORA | Ormat Technologies, Inc. | Increased | $52.3M | 0.46% | 7.7% |
| 75 | TPB | Turning Point Brands, Inc. | New | $52.2M | 0.46% | 7.3% |
| 76 | WGSWWOther Healthcare | GeneDx Holdings Corp. | Decreased | $51.4M | 0.45% | — |
| 77 | ECG | Everus Construction Group, Inc. | Decreased | $50.8M | 0.45% | 4.6% |
| 78 | MYRG | Myr Group Inc. | New | $50.0M | 0.44% | 4.9% |
| 79 | NUVL | Nuvalent Inc. | Increased | $48.6M | 0.43% | 12.2% |
| 80 | BROS | Dutch Bros Inc. | Increased | $48.4M | 0.43% | 65.7% |
| 81 | SAIA | Saia Inc. | Increased | $47.8M | 0.42% | 4.5% |
| 82 | CLS | Celestica Inc. | Decreased | $47.2M | 0.42% | 2.3% |
| 83 | DY | Dycom Industries Inc. | Decreased | $46.7M | 0.41% | 7.2% |
| 84 | ALH | Alliance Laundry Holdings Inc. | New | $44.9M | 0.40% | 9.3% |
| 85 | ADPT | Adaptive Biotechnologies Corporation | Decreased | $44.8M | 0.40% | 7.1% |
| 86 | BE | Bloom Energy Corp. | Decreased | $44.8M | 0.40% | 9.3% |
| 87 | MBX | MBX Biosciences, Inc. | Decreased | $44.4M | 0.39% | 11.9% |
| 88 | ESE | Esco Technologies Inc. | Decreased | $44.0M | 0.39% | 2.3% |
| 89 | GLOB | Globant S.A. | Increased | $43.5M | 0.38% | 14.1% |
| 90 | JBTM | Jbt Marel Corp. | Decreased | $43.3M | 0.38% | 5.0% |
| 91 | TER | Teradyne, Inc. | Increased | $42.8M | 0.38% | 3.6% |
| 92 | PWR | Quanta Services, Inc. | Decreased | $42.7M | 0.38% | 3.6% |
| 93 | CMPSOther Healthcare | COMPASS Pathways plc | Increased | $40.9M | 0.36% | 7.3% |
| 94 | DOO | Brp Inc. | Increased | $40.7M | 0.36% | — |
| 95 | HOOD | Robinhood Markets, Inc. | Increased | $40.4M | 0.36% | 4.2% |
| 96 | AXSM | Axsome Therapeutics Inc. | Decreased | $40.3M | 0.36% | 8.4% |
| 97 | HBM | Hudbay Minerals Inc. | Decreased | $39.3M | 0.35% | — |
| 98 | IMAX | Imax Corp. | Increased | $37.8M | 0.33% | 15.3% |
| 99 | FIX | Comfort Systems Usa Inc. | Decreased | $37.8M | 0.33% | 2.5% |
| 100 | AMLX | Amylyx Pharmaceuticals, Inc. | Increased | $37.6M | 0.33% | 17.3% |
| 101 | CAE | Cae Inc. | Decreased | $36.7M | 0.32% | — |
| 102 | ATROB | Astronics Corp. | Increased | $36.2M | 0.32% | — |
| 103 | SHOO | Steven Madden, Ltd. | New | $35.7M | 0.32% | 9.5% |
| 104 | AEM | Agnico Eagle Mines Ltd. | Decreased | $35.5M | 0.31% | 1.1% |
| 105 | TNDMOther Healthcare | Tandem Diabetes Care Inc. | Increased | $35.4M | 0.31% | 19.1% |
| 106 | TTEK | Tetra Tech Inc. | Increased | $34.8M | 0.31% | 5.5% |
| 107 | CECO | Ceco Environmental Corp. | Increased | $34.7M | 0.31% | 14.5% |
| 108 | TVTX | Travere Therapeutics Inc. | Increased | $34.4M | 0.30% | 18.1% |
| 109 | GIL | Gildan Activewear Inc. | Increased | $33.7M | 0.30% | 3.5% |
| 110 | LIVNOther Healthcare | LivaNova PLC | Decreased | $33.5M | 0.30% | 7.1% |
| 111 | ASND | Ascendis Pharma A/S | Decreased | $33.3M | 0.29% | — |
| 112 | VSCO | Victoria's Secret & Co. | New | $32.6M | 0.29% | 20.8% |
| 113 | RBC | RBC Bearings Inc. | Decreased | $32.5M | 0.29% | 0.9% |
| 114 | IVVD | Invivyd, Inc. | Increased | $32.3M | 0.28% | 11.5% |
| 115 | GPOR | Gulfport Energy Corp. | Decreased | $32.2M | 0.28% | 4.7% |
| 116 | INSPOther Healthcare | Inspire Medical Systems, Inc. | Increased | $32.1M | 0.28% | 13.2% |
| 117 | AXP | American Express CO | Decreased | $31.7M | 0.28% | 2.1% |
| 118 | IESC | IES Holdings, Inc. | Decreased | $30.0M | 0.26% | 11.7% |
| 119 | CAMT | Camtek Ltd. | Increased | $29.9M | 0.26% | 10.4% |
| 120 | LGN | Legence Corp. | New | $29.5M | 0.26% | 6.2% |
| 121 | EVR | Evercore Inc. | Increased | $29.5M | 0.26% | 2.4% |
| 122 | BBNXOther Healthcare | Beta Bionics, Inc. | Decreased | $29.2M | 0.26% | 14.0% |
| 123 | NEO | Neogenomics Inc. | Increased | $29.1M | 0.26% | 8.6% |
| 124 | ALNY | Alnylam Pharmaceuticals Inc. | Increased | $27.7M | 0.24% | 4.8% |
| 125 | LASR | Nlight, Inc. | New | $27.5M | 0.24% | 5.3% |
| 126 | RKLB | Rocket Lab Corp. | New | $27.4M | 0.24% | 5.8% |
| 127 | ARLO | Arlo Technologies, Inc. | Decreased | $27.3M | 0.24% | 11.8% |
| 128 | VCYT | Veracyte, Inc. | Increased | $26.6M | 0.23% | 10.2% |
| 129 | AWI | Armstrong World Industries Inc. | Increased | $26.4M | 0.23% | 2.5% |
| 130 | KNSA | Kiniksa Pharmaceuticals International, plc | Decreased | $26.1M | 0.23% | 9.3% |
| 131 | AMBA | Ambarella Inc. | Decreased | $25.9M | 0.23% | 6.9% |
| 132 | APLD | Applied Digital Corp. | Decreased | $25.6M | 0.23% | 30.4% |
| 133 | FIVE | Five Below, Inc. | Decreased | $25.0M | 0.22% | 3.8% |
| 134 | CELC | Celcuity Inc. | Increased | $24.9M | 0.22% | 27.9% |
| 135 | CDE | Coeur Mining, Inc. | Increased | $24.8M | 0.22% | 3.7% |
| 136 | ATI | Ati Inc. | Increased | $24.5M | 0.22% | 4.2% |
| 137 | PRM | Perimeter Solutions, Inc. | New | $23.9M | 0.21% | 2.6% |
| 138 | AORTOther Healthcare | Artivion, Inc. | Increased | $23.6M | 0.21% | 4.8% |
| 139 | ALM | Almonty Industries Inc. | Decreased | $23.4M | 0.21% | — |
| 140 | XERS | Xeris Biopharma Holdings, Inc. | Increased | $23.4M | 0.21% | 9.5% |
| 141 | NPCEOther Healthcare | NeuroPace Inc. | Increased | $23.3M | 0.21% | 2.6% |
| 142 | FIGS | Figs, Inc. | New | $23.2M | 0.20% | 13.3% |
| 143 | PPTA | Perpetua Resources Corp. | Decreased | $23.2M | 0.20% | 12.1% |
| 144 | LGNZZ | Ligand Pharmaceuticals Inc. | Decreased | $23.1M | 0.20% | — |
| 145 | DQ | Daqo New Energy Corp. | Increased | $23.0M | 0.20% | 6.3% |
| 146 | GHM | Graham Corp. | New | $22.8M | 0.20% | 3.2% |
| 147 | CASY | Caseys General Stores Inc. | Increased | $22.8M | 0.20% | 3.3% |
| 148 | BWXT | BWX Technologies, Inc. | Decreased | $22.5M | 0.20% | 4.4% |
| 149 | ALKS | Alkermes plc | Decreased | $22.3M | 0.20% | 16.5% |
| 150 | MRCY | Mercury Systems Inc. | Increased | $22.2M | 0.20% | 9.2% |
| 151 | WLDN | Willdan Group, Inc. | Increased | $21.8M | 0.19% | 6.5% |
| 152 | PSMT | Pricesmart Inc. | Increased | $21.6M | 0.19% | 8.7% |
| 153 | WWD | Woodward, Inc. | New | $21.4M | 0.19% | 1.5% |
| 154 | DRUG | Bright Minds Biosciences Inc. | Increased | $21.0M | 0.19% | 10.0% |
| 155 | ALNT | Allient Inc. | New | $20.8M | 0.18% | 6.6% |
| 156 | NBIX | Neurocrine Biosciences Inc. | Increased | $20.6M | 0.18% | 7.8% |
| 157 | AR | Antero Resources Corp. | Increased | $20.1M | 0.18% | 2.7% |
| 158 | LPTH | Lightpath Technologies Inc. | New | $19.9M | 0.18% | 6.0% |
| 159 | ROKU | Roku, Inc. | Increased | $19.5M | 0.17% | 6.5% |
| 160 | PRLB | Proto Labs Inc. | New | $19.3M | 0.17% | 3.7% |
| 161 | AMD | Advanced Micro Devices Inc. | Increased | $19.2M | 0.17% | 2.2% |
| 162 | UUUU | Energy Fuels Inc. | Decreased | $19.1M | 0.17% | 15.0% |
| 163 | AMPX-WT | Amprius Technologies, Inc. | Decreased | $18.9M | 0.17% | — |
| 164 | INSM | Insmed Incorporated | Increased | $18.4M | 0.16% | 7.7% |
| 165 | NP | Neptune Insurance Holdings Inc. | New | $18.1M | 0.16% | 20.1% |
| 166 | ASTS | AST SpaceMobile, Inc. | Decreased | $17.9M | 0.16% | 21.3% |
| 167 | ANDG | Andersen Group Inc. | New | $17.9M | 0.16% | 17.1% |
| 168 | AGYS | Agilysys Inc. | Decreased | $17.7M | 0.16% | 4.7% |
| 169 | OPLN | Openlane, Inc. | Decreased | $17.5M | 0.15% | 1.8% |
| 170 | FRQN | Frequency Holdings, Inc. | New | $16.9M | 0.15% | — |
| 171 | FEIM | Frequency Electronics Inc. | New | $16.9M | 0.15% | 12.7% |
| 172 | TCMDOther Healthcare | Tactile Systems Technology Inc. | Increased | $16.4M | 0.14% | 8.2% |
| 173 | DLTR | Dollar Tree, Inc. | New | $16.4M | 0.14% | 7.5% |
| 174 | AFRM | Affirm Holdings, Inc. | Decreased | $16.2M | 0.14% | 6.5% |
| 175 | HLIO | Helios Technologies, Inc. | Increased | $15.8M | 0.14% | 3.5% |
| 176 | MAZE | Maze Therapeutics, Inc. | $15.7M | 0.14% | 8.9% | |
| 177 | LOPE | Grand Canyon Education, Inc. | Decreased | $15.6M | 0.14% | 5.0% |
| 178 | GRDNOther Healthcare | Guardian Pharmacy Services, Inc. | Decreased | $15.2M | 0.13% | 10.3% |
| 179 | AMRC | Ameresco, Inc. | Increased | $14.8M | 0.13% | 14.2% |
| 180 | GMEDOther Healthcare | Globus Medical Inc. | Increased | $14.6M | 0.13% | 3.0% |
| 181 | LCII | Lci Industries | Increased | $14.4M | 0.13% | 13.5% |
| 182 | W | Wayfair Inc. | Increased | $14.4M | 0.13% | 21.1% |
| 183 | CELH | Celsius Holdings, Inc. | Decreased | $14.4M | 0.13% | 9.1% |
| 184 | CPS | Cooper-Standard Holdings Inc. | Increased | $14.4M | 0.13% | 3.9% |
| 185 | ARGX | argenx SE | Decreased | $14.2M | 0.13% | 3.3% |
| 186 | FSLY | Fastly, Inc. | Increased | $14.1M | 0.12% | 14.1% |
| 187 | PODDOther Healthcare | Insulet Corp. | Decreased | $14.0M | 0.12% | 4.8% |
| 188 | ALSN | Allison Transmission Holdings Inc. | Increased | $14.0M | 0.12% | 4.2% |
| 189 | DXPE | Dxp Enterprises Inc. | Decreased | $13.9M | 0.12% | 4.3% |
| 190 | TDY | Teledyne Technologies Inc. | Increased | $13.8M | 0.12% | 3.1% |
| 191 | JBIO | Jade Biosciences, Inc. | Decreased | $13.7M | 0.12% | 8.2% |
| 192 | CGNT | Cognyte Software Ltd. | Increased | $13.5M | 0.12% | 0.8% |
| 193 | XZO | Exzeo Group, Inc. | New | $13.3M | 0.12% | 3.9% |
| 194 | IFS | Intercorp Financial Services Inc. | Decreased | $13.2M | 0.12% | 0.9% |
| 195 | LBRT | Liberty Energy Inc. | Increased | $13.1M | 0.12% | 11.6% |
| 196 | SWIM | Latham Group, Inc. | Decreased | $13.0M | 0.11% | 5.8% |
| 197 | LTH | Life Time Group Holdings, Inc. | Decreased | $13.0M | 0.11% | 6.8% |
| 198 | ABCL | AbCellera Biologics Inc. | Increased | $12.9M | 0.11% | 18.9% |
| 199 | INCY | Incyte Corporation | Increased | $12.7M | 0.11% | 9.8% |
| 200 | LAUR | Laureate Education, Inc. | Decreased | $12.6M | 0.11% | 5.1% |
| 201 | CAHOther Healthcare | Cardinal Health Inc. | Increased | $12.3M | 0.11% | 2.9% |
| 202 | GENI | Genius Sports Ltd. | Decreased | $11.5M | 0.10% | 7.3% |
| 203 | DSGN | Design Therapeutics, Inc. | Increased | $11.1M | 0.10% | 4.8% |
| 204 | WT | WisdomTree, Inc. | Decreased | $10.7M | 0.09% | 20.9% |
| 205 | INOD | Innodata Inc. | Decreased | $10.5M | 0.09% | 16.8% |
| 206 | HUT | Hut 8 Corp. | Decreased | $10.0M | 0.09% | 16.8% |
| 207 | UTI | Universal Technical Institute Inc. | Increased | $9.6M | 0.09% | 5.9% |
| 208 | MAMA | Mama's Creations, Inc. | New | $9.6M | 0.08% | 8.5% |
| 209 | RLMD | Relmada Therapeutics, Inc. | Increased | $9.1M | 0.08% | 5.4% |
| 210 | GWRE | Guidewire Software, Inc. | Decreased | $8.7M | 0.08% | 6.0% |
| 211 | VITL | Vital Farms, Inc. | Decreased | $8.2M | 0.07% | 47.5% |
| 212 | HLMN | Hillman Solutions Corp. | Decreased | $8.1M | 0.07% | 2.6% |
| 213 | AS | Amer Sports, Inc. | Decreased | $7.7M | 0.07% | 8.5% |
| 214 | ATAT | Atour Lifestyle Holdings Ltd. | Increased | $7.6M | 0.07% | 1.8% |
| 215 | KFIIU | K&F Growth Acquisition Corp. II | Increased | $7.5M | 0.07% | — |
| 216 | AGX | Argan Inc. | Decreased | $7.5M | 0.07% | 6.6% |
| 217 | BRCB | Black Rock Coffee Bar, Inc. | Increased | $7.5M | 0.07% | 11.1% |
| 218 | BEAGR | Bold Eagle Acquisition Corp. | Decreased | $7.2M | 0.06% | — |
| 219 | PTRN | Pattern Group Inc. | Decreased | $7.1M | 0.06% | 5.3% |
| 220 | BEIGF | BeOne Medicines Ltd. | Increased | $7.1M | 0.06% | — |
| 221 | PRTO | Protara Therapeutics, Inc. | Increased | $6.7M | 0.06% | — |
| 222 | UAMY | United States Antimony Corp. | New | $6.5M | 0.06% | 21.7% |
| 223 | CNNE | Cannae Holdings, Inc. | Decreased | $6.5M | 0.06% | 12.5% |
| 224 | WSC | WillScot Holdings Corp. | Decreased | $6.0M | 0.05% | 22.3% |
| 225 | ANIP | Ani Pharmaceuticals Inc. | Decreased | $6.0M | 0.05% | 19.0% |
| 226 | TBBB | Bbb Foods Inc. | Increased | $6.0M | 0.05% | 8.4% |
| 227 | ANRO | Alto Neuroscience, Inc. | New | $6.0M | 0.05% | 7.5% |
| 228 | GDEN | Golden Entertainment, Inc. | $6.0M | 0.05% | 4.0% | |
| 229 | TE-WT | T1 Energy Inc. | New | $5.6M | 0.05% | — |
| 230 | INVLW | Innventure, Inc. | New | $5.3M | 0.05% | — |
| 231 | GXO | GXO Logistics, Inc. | $5.2M | 0.05% | 5.0% | |
| 232 | HVMCW | Highview Merger Corp. | New | $5.0M | 0.04% | — |
| 233 | BLFY | Blue Foundry Bancorp | $5.0M | 0.04% | — | |
| 234 | GOOG | Alphabet Inc. | Decreased | $4.4M | 0.04% | — |
| 235 | WLACU | Willow Lane Acquisition Corp. | New | $4.0M | 0.04% | — |
| 236 | NVDA | Nvidia Corp. | Decreased | $3.6M | 0.03% | 1.2% |
| 237 | CBIO | Crescent Biopharma, Inc. | $3.6M | 0.03% | 18.5% | |
| 238 | SION | Sionna Therapeutics, Inc. | $3.5M | 0.03% | 15.2% | |
| 239 | PENN | PENN Entertainment, Inc. | Increased | $3.4M | 0.03% | 17.3% |
| 240 | DTIL | Precision Biosciences Inc. | New | $3.3M | 0.03% | 5.0% |
| 241 | RNA | Avidity Biosciences Inc. | Decreased | $3.3M | 0.03% | — |
| 242 | GSHRW | Gesher Acquisition Corp. II | Decreased | $3.3M | 0.03% | — |
| 243 | DNMXW | Dynamix Corp III | Increased | $3.0M | 0.03% | — |
| 244 | FULC | Fulcrum Therapeutics Inc. | New | $2.8M | 0.02% | 15.1% |
| 245 | AAPL | Apple Inc. | Increased | $2.7M | 0.02% | 0.9% |
| 246 | PTN | Palatin Technologies Inc. | New | $2.6M | 0.02% | 9.0% |
| 247 | APXTW | Apex Treasury Corp. | New | $2.5M | 0.02% | — |
| 248 | CLYM | Climb Bio, Inc. | Increased | $2.4M | 0.02% | 5.2% |
| 249 | MNPR | Monopar Therapeutics | Decreased | $2.2M | 0.02% | 36.5% |
| 250 | PEPG | PepGen Inc. | $2.1M | 0.02% | 6.7% | |
| 251 | LRMR | Larimar Therapeutics, Inc. | $2.0M | 0.02% | 10.9% | |
| 252 | LATAW | Galata Acquisition Corp. II | New | $2.0M | 0.02% | — |
| 253 | LATAU | Galata Acquisition Corp. II | New | $2.0M | 0.02% | — |
| 254 | VYLD | Jpmorgan Chase & CO | Increased | $2.0M | 0.02% | — |
| 255 | MSFT | Microsoft Corp. | Decreased | $1.9M | 0.02% | 1.1% |
| 256 | GDHLF | GDS Holdings Ltd. | Increased | $1.8M | 0.02% | — |
| 257 | ALXO | Alx Oncology Holdings Inc. | Increased | $1.6M | 0.01% | 1.7% |
| 258 | CAEP | Cantor Equity Partners III, Inc. | Increased | $1.5M | 0.01% | 0.0% |
| 259 | COF-PN | Capital One Financial Corp. | Increased | $1.2M | 0.01% | — |
| 260 | WMT | Walmart Inc. | New | $1.2M | 0.01% | 1.6% |
| 261 | AVGO | Broadcom Inc. | Increased | $1.1M | 0.01% | 1.2% |
| 262 | KO | Coca Cola CO | Increased | $1.1M | 0.01% | 1.0% |
| 263 | XOM | Exxon Mobil Corp. | Decreased | $1.1M | 0.01% | 1.2% |
| 264 | EQT | EQT Corp. | Decreased | $1.0M | 0.01% | 3.4% |
| 265 | APP | AppLovin Corp. | Decreased | $1.0M | 0.01% | 4.3% |
| 266 | BDCIW | BTC Development Corp. | New | $1.0M | 0.01% | — |
| 267 | SHOP | Shopify Inc. | Decreased | $958K | 0.01% | 1.8% |
| 268 | META | Meta Platforms, Inc. | Increased | $938K | 0.01% | 1.3% |
| 269 | LIN | Linde Plc | Decreased | $916K | 0.01% | 1.4% |
| 270 | AZN | Astrazeneca Plc | Increased | $899K | 0.01% | 0.1% |
| 271 | LLY | Eli Lilly & Co | Increased | $884K | 0.01% | 0.9% |
| 272 | BA-PA | Boeing CO | Decreased | $827K | 0.01% | — |
| 273 | PLDGP | Prologis, Inc. | Increased | $752K | 0.01% | — |
| 274 | NGNE | Neurogene Inc. | $675K | 0.01% | 32.2% | |
| 275 | TFC-PR | Truist Financial Corp. | Increased | $660K | 0.01% | — |
| 276 | UNP | Union Pacific Corp. | New | $637K | 0.01% | 5.0% |
| 277 | GILD | Gilead Sciences Inc. | Increased | $618K | 0.01% | 1.9% |
| 278 | NET | Cloudflare, Inc. | Increased | $586K | 0.01% | 3.0% |
| 279 | LRCX | Lam Research Corp. | Decreased | $561K | 0.00% | 2.3% |
| 280 | MRK | Merck & Co., Inc. | Increased | $553K | 0.00% | 1.1% |
| 281 | KEYS | Keysight Technologies, Inc. | New | $535K | 0.00% | 1.3% |
| 282 | VEEVOther Healthcare | Veeva Systems Inc. | Increased | $529K | 0.00% | 3.9% |
| 283 | CGNX | Cognex Corp. | New | $507K | 0.00% | 3.7% |
| 284 | INTC | Intel Corp. | New | $505K | 0.00% | 2.8% |
| 285 | TYL | Tyler Technologies Inc. | New | $504K | 0.00% | 4.5% |
| 286 | HCMAW | Hcm Iii Acquisition Corp. | New | $503K | 0.00% | — |
| 287 | DYORU | Insight Digital Partners II | New | $496K | 0.00% | — |
| 288 | WELL | Welltower Inc. | Decreased | $468K | 0.00% | 2.8% |
| 289 | ALAB | Astera Labs, Inc. | Decreased | $451K | 0.00% | 11.1% |
| 290 | BSXOther Healthcare | Boston Scientific Corp. | Decreased | $372K | 0.00% | 1.7% |
| 291 | CEG | Constellation Energy Corp. | Decreased | $360K | 0.00% | 3.2% |
| 292 | SPY | Spdr S&P 500 Etf Trust | New | $316K | 0.00% | — |
| 293 | CCXIW | Churchill Capital Corp XI | Increased | $230K | 0.00% | — |
Top Movers This Quarter
Share changes reflect active decisions. Value changes include price moves.
Frequently asked questions
What stocks did Driehaus Capital own in Q4 2025?
Driehaus Capital held 293 biotech stocks in their 13F portfolio in Q4 2025. Their top positions include CRNX, PRAX, GH, XENE, PL-WT. The full holdings table is available on BiotechEdge with position sizes, quarter-over-quarter changes, and AI analysis.
How much was Driehaus Capital's portfolio worth in Q4 2025?
Driehaus Capital's tracked biotech portfolio was worth $11.3B across 293 positions, with total assets under management of approximately $28B. Portfolio values are based on 13F filings with the SEC.
What did Driehaus Capital buy in Q4 2025?
Driehaus Capital initiated 46 new positions in Q4 2025, including PL-WT, PL, TPB, MYRG, ALH and 41 more. They also increased 128 existing positions.
What did Driehaus Capital sell in Q4 2025?
Driehaus Capital fully exited 487 positions in Q4 2025, including FDX, FIVN, AVB, PGYWW, RXST and 482 more. They also trimmed 110 existing positions.
Is Driehaus Capital a biotech fund?
Growth-oriented investment firm founded by Richard Driehaus (d. 2021), now led by CEO Steve Weber. Michael Caldwell manages the healthcare/life sciences portfolio, applying growth-at-a-reasonable-price philosophy to biotech with a focus on companies with accelerating revenue growth and approaching commercial inflection points.
Want AI analysis, insider signals, and catalyst overlays for Driehaus Capital?
View latest Driehaus Capitalportfolio →