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The Biotech Stocks With the Most Bullish Signals Right Now

Signal Score Rankings

Biotech stocks ranked by a composite signal combining fund convergence, insider buying, catalyst proximity, short interest, and cash runway safety. Higher scores mean more of biotech's smartest indicators are pointing in the same direction — funds buying, insiders buying, catalysts approaching.

How signal scoring works
How is the BiotechEdge signal score calculated?

The signal score (0-200) is a weighted composite of five independent data sources: fund convergence (how many specialist hedge funds hold the stock), insider buying (Form 4 open market purchases), catalyst proximity (days until FDA decision or data readout), short interest (contrarian pressure), and cash runway safety (dilution risk). Each component contributes points, and higher scores mean more signals are aligning.

What does fund convergence mean?

Fund convergence measures how many specialist biotech hedge funds independently hold the same stock. When 3 or more concentrated portfolio managers — like Baker Brothers, Perceptive, or RA Capital — all build positions in one company, it signals strong institutional conviction. These aren't index funds; they're active stock pickers doing deep due diligence.

Why combine multiple signals into one score?

Individual signals can be noisy — a single insider buy or one fund holding doesn't tell you much. But when a stock has multiple funds buying, an insider purchase, and an approaching catalyst, the probability of each signal being noise drops dramatically. The composite score surfaces stocks where independent signals are converging.

What score indicates a strong buy signal?

Scores above 100 indicate strong multi-signal alignment. These stocks typically have 3+ specialist funds holding, recent insider buying, and an approaching catalyst. Scores above 150 are rare and represent the highest-conviction setups in our dataset. The score is a research starting point, not investment advice.

548 ranked companies31 strong signals (score 100+)144 with upcoming catalystScores range from 0–200. 100+ = strong alignment across fund, insider, and catalyst signals.
#TickerFundsScore
1WVE5
145Strong
2LENZ3
140Strong
3TNGX6
125Strong
4OCUL4
121Strong
5ORKA5
120Strong
6DYN5
118Strong
7CELC8
117Strong
8ALKS4
113Strong
9STOK4
112Strong
10AAVXF4
110Strong
11TVTX4
110Strong
12SYRE7
110Strong
13CNTA6
110Strong
14APLS5
109Strong
15PRAX8
108Strong
16APGE4
108Strong
17PTCT5
107Strong
18ARWR5
106Strong
19COGT5
106Strong
20ZBIO1
106Strong
21EWTX5
105Strong
22OLMA5
105Strong
23JANX4
104Strong
24IMVT4
104Strong
25NRIX5
103Strong
26INSP5
102Strong
27IMNM3
101Strong
28IONS3
101Strong
29NUVL5
100Strong
30KYMR6
100Strong
31BBIO5
100Strong
32GRAL4
98Moderate
33IRON6
98Moderate
34PALI4
98Moderate
35TARS5
97Moderate
36TERN4
97Moderate
37FDMT3
96Moderate
38CYTK4
96Moderate
39ENGNW4
95Moderate
40BCRX6
95Moderate
41PCVX6
95Moderate
42CMPS6
95Moderate
43VSTM3
95Moderate
44AMLX4
94Moderate
45CBIO4
92Moderate
46IMCR3
92Moderate
47IVVD5
91Moderate
48CLDX3
91Moderate
49INCY3
90Moderate
50MNPR3
90Moderate
Showing 50 of 548

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